La fibromialgia deja de ser invisible

ORIGEN: http://gineblog.lacoctelera.net/post/2008/11/10/la-fibromialgia-deja-ser-invisible

La fibromialgia se ha considerado como una enfermedad psicosomática o como una simulación hipocondriaca sin base orgánica. Otras veces se considera como una enfermedad reumatológica. Las autoridades laborales no quieren considerarla com enfermedad por la repercusióneconómica que puede acarrear.

Mediante la técnica de tomografía computarizada de emisión de fotón (SPECT), investigadores franceses han sido capaces de detectar aleraciones en ciertas regiones cerebrales de pacientes diagnosticados de fibromialgia. Los hallazgos refuerzan la idea de que existe una alteración de los núcleos cerebrales que procesan el dolor. El Dr. Eric Guedj, dice que la enfermedad se ha considerado como "invisible" pero ahora se dispone de datos objetivos indicando aleraciones en la perfusión de ciertas zonas cerebrales. El estudio se baso en 20 casos de mujeres con fibromialgia y 10 varones sanos sometidos a exploración SPECT.

Guedj E, Cammilleri S, Niboyet J, Dupont P, Vidal E, Dropinski JP, Mundler O. Clinical Correlate of Brain SPECT Perfusion Abnormalities in Fibromyalgia. J Nucl Med. 2008 Nov;49(11):1798-803.

Service Central de Biophysique et de Médecine Nucléaire, AP-HM Timone, Marseille, France; and 2Unité d'Etude et de Traitement de la Douleur, Clinique La Phocéanne, Marseille, France.

The purpose of this study was to investigate the specific clinical correlate of brain SPECT perfusion abnormalities reported in fibromyalgia. METHODS: We performed a whole-brain voxel-based correlation analysis involving regional cerebral blood flow and various parameters related to pain (Visual Analog Scale, Tubingen Pain Behavior Scale, and Questionnaire Douleur de Saint-Antoine Scale), disability (Fibromyalgia Impact Questionnaire [FIQ]), and anxiety and depression status (Hospital Anxiety and Depression scale) in 20 patients with fibromyalgia (P voxel < 0.005). Ten healthy control women were also included, in order to determine areas of significant hypo- and hyperperfusions in patients. RESULTS: FIQ total score was positively correlated with bilateral parietal perfusion, including postcentral cortex. These clusters of correlation were included in the areas of significant hyperperfusion. FIQ total score was also negatively correlated with perfusion of a left anterior temporal cluster, included in the areas of significant hypoperfusions. No other clinical correlation was observed with regional cerebral blood flow. CONCLUSION: These results show that brain perfusion abnormalities in patients with fibromyalgia are correlated with the clinical severity of the disease.